Alvin R. King, Ph.D.
Affiliations: | Pharmacology and Toxicology - Ph.D. | University of California, Irvine, Irvine, CA |
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"Alvin King"Mean distance: 14.22 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Daniele Piomelli | grad student | 2009 | UC Irvine | |
| (Pharmacology and characterization of the endocannabinoid-metabolizing enzyme monoacylglycerol lipase.) | ||||
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Publications
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| King AR, Dotsey EY, Lodola A, et al. (2009) Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chemistry & Biology. 16: 1045-52 |
| Clapper JR, Vacondio F, King AR, et al. (2009) A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo. Chemmedchem. 4: 1505-13 |
| King AR, Lodola A, Carmi C, et al. (2009) A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors. British Journal of Pharmacology. 157: 974-83 |
| Vacondio F, Silva C, Lodola A, et al. (2009) Cover Picture: Structure-Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability / A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo (ChemMedChem 9/2009) Chemmedchem. 4: 1385-1385 |
| Justinova Z, Mangieri RA, Bortolato M, et al. (2008) Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. Biological Psychiatry. 64: 930-7 |
| Mor M, Lodola A, Rivara S, et al. (2008) Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates. Journal of Medicinal Chemistry. 51: 3487-98 |
| King AR, Duranti A, Tontini A, et al. (2007) URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chemistry & Biology. 14: 1357-65 |
| Tarzia G, Antonietti F, Duranti A, et al. (2007) Identification of a bioactive impurity in a commercial sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754). Annali Di Chimica. 97: 887-94 |