Jason R. Clapper, Ph.D.
Affiliations: | University of California, Irvine, Irvine, CA |
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"Jason Clapper"Mean distance: 14.22 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Daniele Piomelli | grad student | 2009 | UC Irvine | |
| (Fatty-acid amide hydrolase inhibitors as analgesics.) | ||||
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Publications
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| Clapper JR, Henry CL, Niphakis MJ, et al. (2018) Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators. The Journal of Pharmacology and Experimental Therapeutics |
| Cisar JS, Weber OD, Clapper JR, et al. (2018) Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders. Journal of Medicinal Chemistry |
| Jung KM, Clapper JR, Fu J, et al. (2012) 2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism. Cell Metabolism. 15: 299-310 |
| Vacondio F, Silva C, Lodola A, et al. (2011) Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability. European Journal of Medicinal Chemistry. 46: 4466-73 |
| Clapper JR, Moreno-Sanz G, Russo R, et al. (2010) Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. Nature Neuroscience. 13: 1265-70 |
| Eisenstein SA, Clapper JR, Holmes PV, et al. (2010) A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 61: 419-29 |
| Clapper JR, Vacondio F, King AR, et al. (2009) A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo. Chemmedchem. 4: 1505-13 |
| Vacondio F, Silva C, Lodola A, et al. (2009) Structure-property relationships of a class of carbamate-based fatty acid amide hydrolase (FAAH) inhibitors: chemical and biological stability. Chemmedchem. 4: 1495-504 |
| Clapper JR, Mangieri RA, Piomelli D. (2009) The endocannabinoid system as a target for the treatment of cannabis dependence. Neuropharmacology. 56: 235-43 |
| Vacondio F, Silva C, Lodola A, et al. (2009) Cover Picture: Structure-Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability / A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo (ChemMedChem 9/2009) Chemmedchem. 4: 1385-1385 |