John Koren, Ph.D.

Affiliations: 
Medical Sciences University of South Florida, Tampa, FL, United States 
Area:
Alzheimer\'s disease
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"John Koren"
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Parents

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Chad A. Dickey grad student 2012 University of South Florida
 (The Role of Hsp70 in Cancer: A Study of the Hsp70 / Akt Relationship.)
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Publications

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Darling AL, Breydo L, Rivas EG, et al. (2019) Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins. International Journal of Biological Macromolecules
Sabbagh JJ, Cordova RA, Zheng D, et al. (2018) Targeting the FKBP51/GR/Hsp90 complex to identify functionally relevant treatments for depression and PTSD. Acs Chemical Biology
Huard DJ, Crowley VM, Du Y, et al. (2018) Trifunctional high-throughput screen identifies promising scaffold to inhibit Grp94 and treat myocilin-associated glaucoma. Acs Chemical Biology
Criado-Marrero M, Rein T, Binder EB, et al. (2018) Hsp90 and FKBP51: complex regulators of psychiatric diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373
Shelton LB, Koren J, Blair LJ. (2017) Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies. Frontiers in Neuroscience. 11: 724
Stothert AR, Suntharalingam A, Tang X, et al. (2017) Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma. Scientific Reports. 7: 17951
Shelton LB, Baker JD, Zheng D, et al. (2017) Hsp90 activator Aha1 drives production of pathological tau aggregates. Proceedings of the National Academy of Sciences of the United States of America
Baker JD, Shelton LB, Zheng D, et al. (2017) Human cyclophilin 40 unravels neurotoxic amyloids. Plos Biology. 15: e2001336
Zong H, Gozman A, Caldas-Lopes E, et al. (2015) A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species. Cell Reports
Azoitei N, Diepold K, Brunner C, et al. (2014) HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization. Cancer Research. 74: 7125-36
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