Elizabeth A. Lipscomb, Ph.D.

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Developmental Cell Ceath in the Nervous System
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"Elizabeth Lipscomb"
Mean distance: 18.16 (cluster 11)
 
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Robert S. Freeman grad student 2001 Rochester
 (The role of SM-20 in neuronal cell death.)
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Publications

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Yoon SO, Shin S, Lipscomb EA. (2006) A novel mechanism for integrin-mediated ras activation in breast carcinoma cells: the alpha6beta4 integrin regulates ErbB2 translation and transactivates epidermal growth factor receptor/ErbB2 signaling. Cancer Research. 66: 2732-9
Mercurio AM, Lipscomb EA, Bachelder RE. (2005) Non-angiogenic functions of VEGF in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 10: 283-90
Lipscomb EA, Simpson KJ, Lyle SR, et al. (2005) The alpha6beta4 integrin maintains the survival of human breast carcinoma cells in vivo. Cancer Research. 65: 10970-6
Chung J, Yoon SO, Lipscomb EA, et al. (2004) The Met receptor and alpha 6 beta 4 integrin can function independently to promote carcinoma invasion. The Journal of Biological Chemistry. 279: 32287-93
Lipscomb EA, Dugan AS, Rabinovitz I, et al. (2003) Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells. Clinical & Experimental Metastasis. 20: 569-76
Freeman RS, Hasbani DM, Lipscomb EA, et al. (2003) SM-20, EGL-9, and the EGLN family of hypoxia-inducible factor prolyl hydroxylases. Molecules and Cells. 16: 1-12
Straub JA, Lipscomb EA, Yoshida ES, et al. (2003) Induction of SM-20 in PC12 cells leads to increased cytochrome c levels, accumulation of cytochrome c in the cytosol, and caspase-dependent cell death. Journal of Neurochemistry. 85: 318-28
Chung J, Bachelder RE, Lipscomb EA, et al. (2002) Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells. The Journal of Cell Biology. 158: 165-74
Lipscomb EA, Sarmiere PD, Freeman RS. (2001) SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons. The Journal of Biological Chemistry. 276: 5085-92
Lipscomb EA, Sarmiere PD, Crowder RJ, et al. (1999) Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons. Journal of Neurochemistry. 73: 429-32
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