David J. Lomb, Ph.D.
Affiliations: | University of Rochester, Rochester, NY |
Area:
Developmental Cell Ceath in the Nervous SystemGoogle:
"David Lomb"Mean distance: 18.16 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentorRobert S. Freeman | grad student | 2007 | Rochester | |
(The HIF prolyl hydroxylase inhibitors DMOG and DHB delay neuronal cell death caused by trophic factor deprivation through a HIF-1alpha-independent, glucose-dependent mechanism.) |
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Publications
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Lomb DJ, Desouza LA, Franklin JL, et al. (2009) Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetic neurons. Molecular Pharmacology. 75: 1198-209 |
Lomb DJ, Straub JA, Freeman RS. (2007) Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation. Journal of Neurochemistry. 103: 1897-906 |
Freeman RS, Burch RL, Crowder RJ, et al. (2004) NGF deprivation-induced gene expression: after ten years, where do we stand? Progress in Brain Research. 146: 111-26 |