Audrey Fischer, Ph.D.

Affiliations: 
Biology University of California, San Diego, La Jolla, CA 
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"Audrey Fischer"
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Mauricio Montal grad student 2008 UCSD
 (Chaperone function of the botulinum neurotoxin protein translocating channel.)
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Publications

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Fischer A, Wolman M, Granato M, et al. (2015) Carbamate nerve agent prophylatics exhibit distinct toxicological effects in the zebrafish embryo model. Neurotoxicology and Teratology. 50: 1-10
Fischer AE, Wu SK, Proescher JB, et al. (2015) A high-throughput drop microfluidic system for virus culture and analysis. Journal of Virological Methods. 213: 111-7
Kolawole AO, Li M, Xia C, et al. (2014) Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization. Journal of Virology. 88: 4543-57
Fischer A, Montal M. (2013) Molecular dissection of botulinum neurotoxin reveals interdomain chaperone function. Toxicon : Official Journal of the International Society On Toxinology. 75: 101-7
Fischer A, Sambashivan S, Brunger AT, et al. (2012) Beltless translocation domain of botulinum neurotoxin A embodies a minimum ion-conductive channel. The Journal of Biological Chemistry. 287: 1657-61
Fischer A, Holden MA, Pentelute BL, et al. (2011) Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers. Proceedings of the National Academy of Sciences of the United States of America. 108: 16577-81
Janowiak BE, Fischer A, Collier RJ. (2010) Effects of introducing a single charged residue into the phenylalanine clamp of multimeric anthrax protective antigen. The Journal of Biological Chemistry. 285: 8130-7
Vernier G, Wang J, Jennings LD, et al. (2009) Solubilization and characterization of the anthrax toxin pore in detergent micelles. Protein Science : a Publication of the Protein Society. 18: 1882-95
Wang J, Vernier G, Fischer A, et al. (2009) Functions of phenylalanine residues within the beta-barrel stem of the anthrax toxin pore. Plos One. 4: e6280
Fischer A, Nakai Y, Eubanks LM, et al. (2009) Bimodal modulation of the botulinum neurotoxin protein-conducting channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 1330-5
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