Ksenia A. Orlova, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Epilepsy (Tuberous Sclerosis)
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"Ksenia Orlova"
Mean distance: 20.17 (cluster 17)
 

Parents

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Peter Crino grad student 2009 Penn
 (The function of STRADalpha during corticogenesis: Insights into the neuropathogenesis of focal cortical dysplasias.)
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Publications

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Tsai V, Parker WE, Orlova KA, et al. (2014) Fetal brain mTOR signaling activation in tuberous sclerosis complex. Cerebral Cortex (New York, N.Y. : 1991). 24: 315-27
Parker WE, Orlova KA, Parker WH, et al. (2013) Rapamycin prevents seizures after depletion of STRADA in a rare neurodevelopmental disorder. Science Translational Medicine. 5: 182ra53
Parker WE, Orlova KA, Heuer GG, et al. (2011) Enhanced epidermal growth factor, hepatocyte growth factor, and vascular endothelial growth factor expression in tuberous sclerosis complex. The American Journal of Pathology. 178: 296-305
Orlova KA, Tsai V, Baybis M, et al. (2010) Early progenitor cell marker expression distinguishes type II from type I focal cortical dysplasias. Journal of Neuropathology and Experimental Neurology. 69: 850-63
Hamamdzic D, Fenning RS, Patel D, et al. (2010) Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease. American Journal of Physiology. Heart and Circulatory Physiology. 299: H699-706
Orlova KA, Parker WE, Heuer GG, et al. (2010) STRADalpha deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice. The Journal of Clinical Investigation. 120: 1591-602
Orlova KA, Crino PB. (2010) The tuberous sclerosis complex. Annals of the New York Academy of Sciences. 1184: 87-105
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