Kevin Woolfrey

Affiliations: 
Northwestern University, Evanston, IL 
Area:
neural development, neural migration
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"Kevin Woolfrey"
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Joshua A. Burk grad student William and Mary
Peter Penzes grad student 2010 Northwestern
 (The role of Epac2 in the structure and function of cortical spiny synapses and its contribution to the pathophysiology of autism.)
Mark Louis Dell'Acqua post-doc Northwestern
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Publications

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Martinez TP, Larsen ME, Sullivan E, et al. (2024) Amyloid-β-induced dendritic spine elimination requires Ca-permeable AMPA receptors, AKAP-Calcineurin-NFAT signaling, and the NFAT target gene Mdm2. Eneuro
Jones KA, Sumyia M, Woolfrey KM, et al. (2019) Loss of EPAC2 alters dendritic spine morphology and inhibitory synapse density. Molecular and Cellular Neurosciences
Gibson ES, Woolfrey KM, Li H, et al. (2018) Subcellular Localization and Activity of the Mitogen-activated Protein Kinase Kinase 7 (MKK7) γ Isoform are Regulated through Binding to the Phosphatase Calcineurin. Molecular Pharmacology
Purkey AM, Woolfrey KM, Crosby KC, et al. (2018) AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca-Permeable AMPA Receptors to Control LTP. Cell Reports. 25: 974-987.e4
Eisinger KRT, Woolfrey KM, Swanson SP, et al. (2018) Palmitoylation of caveolin-1 is regulated by the same DHHC acyltransferases that modify steroid hormone receptors. The Journal of Biological Chemistry
Dell'Acqua ML, Woolfrey KM. (2018) FRETting over postsynaptic PKC signaling. Nature Neuroscience
Woolfrey KM, O'Leary H, Goodell DJ, et al. (2017) CaMKII regulates the de-palmitoylation and synaptic removal of AKAP79/150 to mediate structural LTD. The Journal of Biological Chemistry
Woolfrey KM, Srivastava DP. (2016) Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases. Neural Plasticity. 2016: 3025948
Woolfrey KM, Dell'Acqua ML. (2015) Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic Plasticity. The Journal of Biological Chemistry
Woolfrey KM, Sanderson JL, Dell'Acqua ML. (2015) The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 442-56
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