Senthilkumar S. Karuppagounder, Ph.D.

Affiliations: 
2002-2004 Biomedical sciences Jadavpur University, Kolkata, West Bengal, India 
 2004-2006 Cell Biology & Physiology Indian inst. of Chemical Engineering 
 2006-2009 Pharmacal Science Auburn University, Auburn, AL, United States 
 2009- Neurology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Area:
Parkinson's Disease, Neurodegeneration, Synaptic Transmission, hippocampal glutamatergic system, AMPA and NMDA channels
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"Senthilkumar S. Karuppagounder"
Mean distance: 16.22 (cluster 6)
 
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Parents

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Muralikrishnan Dhanasekaran grad student 2006-2009 Auburn University
Vishnu Suppiramaniam grad student 2006-2009 Auburn University
 (Environmental toxins and dopaminergic neurotoxicity: Novel neuroprotective strategies.)
Ted M. Dawson post-doc 2009-2015 Johns Hopkins Medical School
Valina L. Dawson post-doc 2009-2015 Johns Hopkins Medical School
Ted M. Dawson research scientist 2015- Johns Hopkins Medical School
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Publications

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Kumar M, Acevedo-Cintrón J, Jhaldiyal A, et al. (2020) Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons. Stem Cell Reports
Pirooznia SK, Yuan C, Khan MR, et al. (2020) PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency. Molecular Neurodegeneration. 15: 17
Kim S, Kwon SH, Kam TI, et al. (2019) Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease. Neuron
Brahmachari S, Lee S, Kim S, et al. (2019) Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease. Brain : a Journal of Neurology
Xue Y, Zhan X, Sun S, et al. (2018) Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons. Stem Cells Translational Medicine
Kam TI, Mao X, Park H, et al. (2018) Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease. Science (New York, N.Y.). 362
Yun SP, Kam TI, Panicker N, et al. (2018) Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease. Nature Medicine
Xiong Y, Neifert S, Karuppagounder SS, et al. (2018) Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Proceedings of the National Academy of Sciences of the United States of America
Kim S, Yun SP, Lee S, et al. (2018) GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers. Proceedings of the National Academy of Sciences of the United States of America
Yun SP, Kim D, Kim S, et al. (2018) α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism. Molecular Neurodegeneration. 13: 1
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