Sokhom S. Pin, Ph.D.
Affiliations: | University of Connecticut, Storrs, CT, United States |
Area:
Neuroprotection in models of Alzheimer-type pathogenesisGoogle:
"Sokhom Pin"Mean distance: 30533.1
Parents
Sign in to add mentor| Ben A. Bahr | grad student | 2007 | University of Connecticut | |
| (Functional desensitization of calcitonin gene -related peptide (CGRP) receptors in SK -N -MC cells.) | ||||
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Publications
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| Sasane R, Bartels A, Field M, et al. (2021) Parkinson disease among patients treated for benign prostatic hyperplasia with α1 adrenergic receptor antagonists. The Journal of Clinical Investigation |
| Mercer SE, Chaturvedula PV, Conway CM, et al. (2020) Azepino-indazoles as calcitonin gene-related peptide (CGRP) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 127624 |
| Bidlack JM, Knapp BI, Deaver DR, et al. (2018) Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being Developed as an Adjunctive Treatment for Major Depressive Disorder. The Journal of Pharmacology and Experimental Therapeutics |
| McKeown SC, Zecri FJ, Fortier E, et al. (2014) The design and implementation of a generic lipopeptide scanning platform to enable the identification of 'locally acting' agonists for the apelin receptor. Bioorganic & Medicinal Chemistry Letters. 24: 4871-5 |
| Dasgupta B, Kozlowski E, Schroeder DR, et al. (2014) Serendipitous oxidation product of BIBN4096BS: a potent CGRP receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 24: 2744-8 |
| Tora G, Degnan AP, Conway CM, et al. (2013) Preparation of imidazoles as potent calcitonin gene-related peptide (CGRP) antagonists. Bioorganic & Medicinal Chemistry Letters. 23: 5684-8 |
| Chaturvedula PV, Mercer SE, Pin SS, et al. (2013) Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery. Bioorganic & Medicinal Chemistry Letters. 23: 3157-61 |
| Han X, Civiello RL, Conway CM, et al. (2013) The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2. Bioorganic & Medicinal Chemistry Letters. 23: 1870-3 |
| Han X, Civiello RL, Conway CM, et al. (2013) Corrigendum to “The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2” [Bioorg. Med. Chem. Lett. 23 (2013) 1870–1873] Bioorganic & Medicinal Chemistry Letters. 23: 3674 |
| Chaturvedula PV, Pin S, Tholady G, et al. (2012) Design and synthesis of potent antagonists containing rigid spirocyclic privileged structures for the CGRP receptor. Bioorganic & Medicinal Chemistry Letters. 22: 4719-22 |