Ohannes K. Melemedjian, Ph.D.

Affiliations: 
Molecular & Cellular Biology University of Arizona, Tucson, AZ 
Area:
Pain
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"Ohannes Melemedjian"
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Josephine Lai grad student 2007 University of Arizona
 (Adverse effects of sustained morphine treatment in an experimental model of bone cancer pain: Mechanisms that underlie hyperalgesia and osteoclastogenesis.)
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Publications

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Da Silva JT, Hernandez-Rojas LG, Mekonen HK, et al. (2023) Sex differences in visceral sensitivity and brain activity in a rat model of comorbid pain: a longitudinal study. Pain
Ludman T, Melemedjian OK. (2019) Bortezomib and metformin opposingly regulate the expression of hypoxia-inducible factor alpha and the consequent development of chemotherapy-induced painful peripheral neuropathy. Molecular Pain. 15: 1744806919850043
Ludman T, Melemedjian OK. (2019) Bortezomib-induced aerobic glycolysis contributes to chemotherapy-induced painful peripheral neuropathy. Molecular Pain. 15: 1744806919837429
Moy JK, Khoutorsky A, Asiedu MN, et al. (2017) The MNK - eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Auh QS, Chun YH, Melemedjian OK, et al. (2016) Peripheral interactions between cannabinoid and opioid receptor agonists in a model of inflammatory mechanical hyperalgesia. Brain Research Bulletin
Melemedjian OK, Khoutorsky A. (2015) Translational control of chronic pain. Progress in Molecular Biology and Translational Science. 131: 185-213
Wei X, Yan J, Tillu D, et al. (2015) Meningeal norepinephrine produces headache behaviors in rats via actions both on dural afferents and fibroblasts. Cephalalgia : An International Journal of Headache
Melemedjian OK, Tillu DV, Moy JK, et al. (2014) Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Molecular Pain. 10: 45
Melemedjian OK, Khoutorsky A, Sorge RE, et al. (2013) mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. Pain. 154: 1080-91
Melemedjian OK, Tillu DV, Asiedu MN, et al. (2013) BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Molecular Pain. 9: 12
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