Isaac H. Solomon, Ph.D.

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
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"Isaac Solomon"
Mean distance: 18 (cluster 11)
 

Parents

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David A. Harris grad student 2013 Washington University
 (Mutant Prion Protein-induced Ion Channel Activity.)
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Publications

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Biasini E, Unterberger U, Solomon IH, et al. (2013) A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2408-18
Solomon IH, Biasini E, Harris DA. (2012) Ion channels induced by the prion protein: mediators of neurotoxicity. Prion. 6: 40-5
Solomon IH, Khatri N, Biasini E, et al. (2011) An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity. The Journal of Biological Chemistry. 286: 14724-36
Solomon IH, Huettner JE, Harris DA. (2010) Neurotoxic mutants of the prion protein induce spontaneous ionic currents in cultured cells. The Journal of Biological Chemistry. 285: 26719-26
Massignan T, Stewart RS, Biasini E, et al. (2010) A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein. The Journal of Biological Chemistry. 285: 7752-65
Solomon IH, Schepker JA, Harris DA. (2010) Prion neurotoxicity: insights from prion protein mutants. Current Issues in Molecular Biology. 12: 51-61
Solomon IH, Hager JM, Safi R, et al. (2005) Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity. Journal of Molecular Biology. 354: 1091-102
Ortlund EA, Lee Y, Solomon IH, et al. (2005) Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP. Nature Structural & Molecular Biology. 12: 357-63
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