Andrea J. Mothe, Ph.D.
Affiliations: | University of Toronto, Toronto, ON, Canada |
Area:
Biomedical EngineeringGoogle:
"Andrea Mothe"Mean distance: 15.86 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentorIan Brown | grad student | 2002 | University of Toronto | |
(Expression of mRNA encoding the related extracellular matrix glycoproteins, SC1 and SPARC, in the developing and adult rat central nervous system.) |
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Publications
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Hachem LD, Hong J, Velumian A, et al. (2023) Excitotoxic glutamate levels drive spinal cord ependymal stem cell proliferation and fate specification through CP-AMPAR signaling. Stem Cell Reports |
Mothe AJ, Jacobson PB, Caprelli M, et al. (2022) Delayed administration of elezanumab, a human anti-RGMa neutralizing monoclonal antibody, promotes recovery following cervical spinal cord injury. Neurobiology of Disease. 105812 |
Jacobson PB, Goody R, Lawrence M, et al. (2021) Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemi-compression spinal cord injury in non-human primates. Neurobiology of Disease. 105385 |
Ahuja CS, Mothe A, Khazaei M, et al. (2020) The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury. Stem Cells Translational Medicine |
Mothe AJ, Coelho M, Huang L, et al. (2020) Delayed administration of the human anti-RGMa monoclonal antibody elezanumab promotes functional recovery including spontaneous voiding after spinal cord injury in rats. Neurobiology of Disease. 104995 |
Hachem LD, Mothe AJ, Tator CH. (2019) Unlocking the Paradoxical Endogenous Stem Cell Response after Spinal Cord Injury. Stem Cells (Dayton, Ohio) |
Caprelli MT, Mothe AJ, Tator C. (2018) Hyperphosphorylated tau as a novel biomarker for traumatic axonal injury in the spinal cord. Journal of Neurotrauma |
Caprelli MT, Mothe AJ, Tator CH. (2017) CNS Injury: Posttranslational Modification of the Tau Protein as a Biomarker. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858417742125 |
Hachem LD, Mothe AJ, Tator CH. (2017) Positive Modulation of AMPA Receptors Promotes Survival and Proliferation of Neural Stem/Progenitor Cells from the Adult Rat Spinal Cord. Stem Cells and Development |
Mothe AJ, Tassew NG, Shabanzadeh AP, et al. (2017) RGMa inhibition with human monoclonal antibodies promotes regeneration, plasticity and repair, and attenuates neuropathic pain after spinal cord injury. Scientific Reports. 7: 10529 |