William R. Marrs, Ph.D.
Institution:
University of Washington, Seattle, Seattle, WAArea:
Cannabinoid signaling and neuroinflammationGoogle:
"William Marrs"Mean distance: 15.48 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Nephi Stella | grad student | 2011 | University of Washington | |
| (The Serine Hydrolase ABHD6 Regulates Endocannabinoid Signaling.) | ||||
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Publications
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| Naydenov AV, Horne EA, Cheah CS, et al. (2014) ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice. Neuron. 83: 361-71 |
| Horne EA, Coy J, Swinney K, et al. (2013) Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models. The European Journal of Neuroscience. 37: 429-40 |
| Marrs WR, Horne EA, Ortega-Gutierrez S, et al. (2011) Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons. The Journal of Biological Chemistry. 286: 28723-8 |
| Marrs WR, Blankman JL, Horne EA, et al. (2010) The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nature Neuroscience. 13: 951-7 |
| Cudaback E, Marrs W, Moeller T, et al. (2010) The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas. Plos One. 5: e8702 |
| Marrs W, Stella N. (2009) Measuring endocannabinoid hydrolysis: refining our tools and understanding. The Aaps Journal. 11: 307-11 |
| Marrs W, Stella N. (2007) 2-AG + 2 new players = forecast for therapeutic advances. Chemistry & Biology. 14: 1309-11 |
| Marrs W, Kuperman J, Avedian T, et al. (2005) Alpha-2 adrenoceptor activation inhibits phencyclidine-induced deficits of spatial working memory in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1500-10 |