Luca Posa, Pharm.D., Ph.D.

2010-2014 Pharmacology Università di Bologna, Bologna, Italy 
 2012-2013 CNRS & Université Paris Descartes 
 2014-2015 Pharmacology CHU Ste. Justine, Universite de Montreal, Montréal, Québec, Canada 
 2015- Psychiatry McGill University, Montreal, QC, Canada 
opioid, melatonin, pain, tolerance
"Luca Posa"
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Posa L, De Gregorio D, He Q, et al. (2022) Supraspinal melatonin MT receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors. Journal of Pineal Research
Rullo L, Posa L, Caputi FF, et al. (2021) Nociceptive behavior and central neuropeptidergic dysregulations in male and female mice of a Fabry disease animal model. Brain Research Bulletin. 175: 158-167
De Gregorio D, Popic J, Enns JP, et al. (2021) Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 118
Caputi FF, Di Cesare Mannelli L, Rullo L, et al. (2020) The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms. Biochemical Pharmacology. 182: 114255
De Gregorio D, Dean Conway J, Canul ML, et al. (2020) Effects of chronic exposure to low doses of Δ9- tetrahydrocannabinol in adolescence and adulthood on serotonin/norepinephrine neurotransmission and emotional behaviors. The International Journal of Neuropsychopharmacology
Posa L, Lopez-Canul M, Rullo L, et al. (2020) Nociceptive responses in MT receptor knockout mice compared to MT and double MT /MT receptor knockout mice. Journal of Pineal Research. e12671
Comai S, De Gregorio D, Posa L, et al. (2020) Dysfunction of serotonergic activity and emotional responses across the light-dark cycle in mice lacking MT receptors. Journal of Pineal Research. e12653
López-Canul M, Min SH, Posa L, et al. (2019) Melatonin MT and MT Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle. International Journal of Molecular Sciences. 20
Lopez-Canul M, Sasson T, Ochoa-Sanchez R, et al. (2019) Effect of the selective melatonin MT1 receptor partial agonist UCM871 in the activity of noraphineprine neurons of the locus coeruleus during the sleep/wake cycle Sleep Medicine. 64: S231
De Gregorio D, Popic J, Enns J, et al. (2019) S.17.02 Lysergic acid diethylamide reverses anxious-like behaviour and modulates serotonergic neurotransmission in a chronic stress model European Neuropsychopharmacology. 29: S12-S13
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