Audrey S. Dickey, Ph.D.
Affiliations: | 2017- | Neurology | Duke University School of Medicine, Durham, NC, United States |
Area:
protein phosphatases, mitochondria, Omics, transcriptome, transcription, autophagy, inflammation, preclinical trial, iPSCsGoogle:
"Audrey Dickey"Mean distance: 15.77 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Stefan Strack | grad student | 2010 | University of Iowa | |
| (Role of PP2A/Bbeta2 and PKA/AKAP1 in brain development and function via dynamin-related protein 1 (Drp1) control of mitochondria shape and bioenergetics.) | ||||
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Publications
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| Flippo KH, Lin Z, Dickey AS, et al. (2020) Deletion of a neuronal Drp1 activator protects against cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
| Gao R, Chakraborty A, Geater C, et al. (2019) Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. Elife. 8 |
| Flippo KH, Gnanasekaran A, Perkins GA, et al. (2018) AKAP1 protects from cerebral ischemic stroke by inhibiting Drp1-dependent mitochondrial fission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
| Dickey AS, La Spada AR. (2017) Therapy development in Huntington disease: From current strategies to emerging opportunities. American Journal of Medical Genetics. Part A |
| Dickey AS, Sanchez DN, Arreola M, et al. (2017) PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science Translational Medicine. 9 |
| Dickey AS, Pineda VV, Tsunemi T, et al. (2015) PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. Nature Medicine |
| Dickey AS, Strack S. (2011) PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15716-26 |
| Merrill RA, Dagda RK, Dickey AS, et al. (2011) Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. Plos Biology. 9: e1000612 |
| Merrill RA, Dagda RK, Dickey AS, et al. (2011) A GTPase-compromised Drp1 mutant accumulates in slowly recycling complexes at mitochondria. Plos Biology |