Heather A. Halem, Ph.D.

Boston University, Boston, MA, United States 
"Heather Halem"
Mean distance: 16.44 (cluster 45)


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Michael Baum grad student 2001 Boston University
 (Pheromonal communication in Balb/c mice: Profile of immediate -early gene induction in the vomeronasal projection pathway.)
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Van der Ploeg L, Laken H, Sharma S, et al. (2014) Preclinical gastrointestinal prokinetic efficacy and endocrine effects of the ghrelin mimetic RM-131. Life Sciences. 109: 20-9
Kievit P, Halem H, Marks DL, et al. (2013) Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques. Diabetes. 62: 490-7
Su X, Halem HA, Thomas MP, et al. (2012) Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors. Bioorganic & Medicinal Chemistry. 20: 6394-402
Pradaux-Caggiano F, Su X, Vicker N, et al. (2012) Synthesis and evaluation of thiadiazole derivatives as inhibitors of 11β-hydroxysteroid dehydrogenase type 1 Medchemcomm. 3: 1117-1124
Palus S, Schur R, Akashi YJ, et al. (2011) Ghrelin and its analogues, BIM-28131 and BIM-28125, improve body weight and regulate the expression of MuRF-1 and MAFbx in a rat heart failure model. Plos One. 6: e26865
Su X, Pradaux-Caggiano F, Vicker N, et al. (2011) Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. Chemmedchem. 6: 1616-29
Su X, Vicker N, Thomas MP, et al. (2011) Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors. Chemmedchem. 6: 1439-51
Pfluger PT, Castañeda TR, Heppner KM, et al. (2011) Ghrelin, peptide YY and their hypothalamic targets differentially regulate spontaneous physical activity. Physiology & Behavior. 105: 52-61
Su X, Pradaux-Caggiano F, Thomas MP, et al. (2010) Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors. Chemmedchem. 5: 1026-44
Kumar KG, Sutton GM, Dong JZ, et al. (2009) Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL/6J mice. Peptides. 30: 1892-900
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