Christopher A. Tobias, Ph.D.

Affiliations: 
Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
neuroscience, spinal cord injury, plasticity
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"Christopher Tobias"
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Parents

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marion murray grad student 2002 Drexel Medical School
 (Developing combination strategies for the treatment of spinal cord injury utilizing ex vivo gene therapy and alginate encapsulation.)
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Publications

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Tobias CA, Han SS, Shumsky JS, et al. (2005) Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. Journal of Neurotrauma. 22: 138-56
Shumsky JS, Tobias CA, Tumolo M, et al. (2003) Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function. Experimental Neurology. 184: 114-30
Tobias CA, Shumsky JS, Shibata M, et al. (2003) Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Experimental Neurology. 184: 97-113
Murray M, Tobias CA. (2003) Regeneration and sprouting in the injured spinal cord: A decade of growth Topics in Spinal Cord Injury Rehabilitation. 8: 37-51
Murray M, Kim D, Liu Y, et al. (2002) Transplantation of genetically modified cells contributes to repair and recovery from spinal injury. Brain Research. Brain Research Reviews. 40: 292-300
Bhowmik M, Tobias CA, Fischer I, et al. (2002) Locomotor recovery promoted by sensorimotor training and the graft of fibroblasts genetically engineered to produce BDNF and NT3 in the injured cat spinal cord Bioengineering, Proceedings of the Northeast Conference. 233-234
Bhowmik M, Tobias CA, Fischer I, et al. (2002) Locomotor recovery promoted by sensorimotor training and the graft of fibroblasts genetically engineered to produce BDNF and NT3 in the injured cat spinal cord Bioengineering, Proceedings of the Northeast Conference. 233-234
Tobias CA, Dhoot NO, Wheatley MA, et al. (2001) Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats. Journal of Neurotrauma. 18: 287-301
Chow SY, Moul J, Tobias CA, et al. (2000) Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord. Brain Research. 874: 87-106
Leith JT, Woodruff KH, Lewinsky BS, et al. (1975) Letter: Tolerance of the spinal cord of rats to irradiation with neon ions. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 28: 393-8
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