Shimon P. Francis, Ph.D.

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
auditory system degeneration
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"Shimon Francis"
Mean distance: 15.93 (cluster 6)
 
SNBCP

Parents

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Lisa L. Cunningham grad student 2011 MUSC
 (Celastrol, a Purified Plant Extract Protects Against Therapeutic Drug-Induced Ototoxicity.)
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Publications

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Breglio AM, May LA, Barzik M, et al. (2020) Exosomes mediate sensory hair cell protection in the inner ear. The Journal of Clinical Investigation
Du TT, Dewey JB, Wagner EL, et al. (2019) LMO7 deficiency reveals the significance of the cuticular plate for hearing function. Nature Communications. 10: 1117
Nicholas BD, Francis S, Wagner EL, et al. (2017) Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity. Frontiers in Cellular Neuroscience. 11: 303
Francis SP, Cunningham LL. (2017) Non-autonomous Cellular Responses to Ototoxic Drug-Induced Stress and Death. Frontiers in Cellular Neuroscience. 11: 252
Francis SP, Krey JF, Krystofiak ES, et al. (2015) A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1999-2014
Baker TG, Roy S, Brandon CS, et al. (2015) Heat shock protein-mediated protection against Cisplatin-induced hair cell death. Journal of the Association For Research in Otolaryngology : Jaro. 16: 67-80
May LA, Kramarenko II, Brandon CS, et al. (2013) Inner ear supporting cells protect hair cells by secreting HSP70. The Journal of Clinical Investigation. 123: 3577-87
Francis SP, Katz J, Fanning KD, et al. (2013) A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3079-93
Francis SP, Kramarenko II, Brandon CS, et al. (2011) Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32. Cell Death & Disease. 2: e195
Polesskaya O, Cunningham LL, Francis SP, et al. (2010) Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure. Hearing Research. 270: 21-7
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