Richard H. Singleton, Ph.D.

Institution:
Virginia Commonwealth University, Richmond, VA, United States
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"Richard Singleton"
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John T. Povlishock grad student 2002 VCU
 (A study of the effects of diffuse brain injury on reactive axonal and neuronal somatic responses.)
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Publications

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Singleton RH, Yan HQ, Fellows-Mayle W, et al. (2010) Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury. Journal of Neurotrauma. 27: 1091-9
Kurz JE, Hamm RJ, Singleton RH, et al. (2005) A persistent change in subcellular distribution of calcineurin following fluid percussion injury in the rat. Brain Research. 1048: 153-60
Singleton RH, Povlishock JT. (2004) Identification and characterization of heterogeneous neuronal injury and death in regions of diffuse brain injury: evidence for multiple independent injury phenotypes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3543-53
Stone JR, Okonkwo DO, Singleton RH, et al. (2002) Caspase-3-mediated cleavage of amyloid precursor protein and formation of amyloid Beta peptide in traumatic axonal injury. Journal of Neurotrauma. 19: 601-14
Singleton RH, Zhu J, Stone JR, et al. (2002) Traumatically induced axotomy adjacent to the soma does not result in acute neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 791-802
Stone JR, Singleton RH, Povlishock JT. (2001) Intra-axonal neurofilament compaction does not evoke local axonal swelling in all traumatically injured axons. Experimental Neurology. 172: 320-31
Suehiro E, Singleton RH, Stone JR, et al. (2001) The immunophilin ligand FK506 attenuates the axonal damage associated with rapid rewarming following posttraumatic hypothermia. Experimental Neurology. 172: 199-210
Singleton RH, Stone JR, Okonkwo DO, et al. (2001) The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury. Journal of Neurotrauma. 18: 607-14
Stone JR, Singleton RH, Povlishock JT. (2000) Antibodies to the C-terminus of the beta-amyloid precursor protein (APP): a site specific marker for the detection of traumatic axonal injury. Brain Research. 871: 288-302
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