Katherine S. Damme
Corticostriatal Connectivity, MRI, DTI, Reward, Bipolar Disorder, Schizophrenia, TMS, EEG, Hormones, Neuroimmunology
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My research integrates neuroimaging techniques to identifying the neural underpinnings of risk taking, reward and motivation. The cortico-striatal network is particularly interesting because of it's transdiagnostic associations, from depression to mania. It even has implications for treatment of other disorders like schizophrenia and drug addiction.
Cortico-striatal network dysregulation underlies some of society’s most costly social problems, including drug use, impulsivity, and risk taking behaviors. My research models both structural (how regions physically connect) and functional (how regions communicate) connectivity in the cortico-striatal network to predicts clinical symptoms and risk for psychopathology. My research also investigates mechanisms by which neuroendocrine and neuroimmunological modulate functional and structural connectivity between cortico-striatal. Finally, I am investigating the manipulations of these network relationships with TMS and tDCS.