Charles L. Howe, Ph.D.

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
neurodegneration, Down syndrome
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"Charles Howe"
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William C. Mobley grad student 2000 UCSF
 (Neutrophic signaling endosomes: Clathrin -coated vesicles propagate the NGF signal through the Ras /MAPK pathway.)
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Publications

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Walker-Caulfield ME, Guo Y, Johnson RK, et al. (2015) NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG. Journal of Neuroinflammation. 12: 185
Howe CL, Kaptzan T, Magaña SM, et al. (2014) Neuromyelitis optica IgG stimulates an immunological response in rat astrocyte cultures Glia. 62: 692-708
Sauer BM, Schmalstieg WF, Howe CL. (2013) Axons are injured by antigen-specific CD8(+) T cells through a MHC class I- and granzyme B-dependent mechanism. Neurobiology of Disease. 59: 194-205
Poland GA, Poland CM, Howe CL. (2013) Influenza vaccine and Guillain-Barré syndrome: making informed decisions. Lancet (London, England). 381: 1437-9
Bergstrom RA, Choi JH, Manduca A, et al. (2013) Automated identification of multiple seizure-related and interictal epileptiform event types in the EEG of mice. Scientific Reports. 3: 1483
Howe CL, Lafrance-Corey RG, Sundsbak RS, et al. (2012) Hippocampal protection in mice with an attenuated inflammatory monocyte response to acute CNS picornavirus infection. Scientific Reports. 2: 545
Howe CL, Lafrance-Corey RG, Sundsbak RS, et al. (2012) Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain. Journal of Neuroinflammation. 9: 50
LaFrance-Corey RG, Howe CL. (2011) Isolation of brain-infiltrating leukocytes. Journal of Visualized Experiments : Jove
German CL, Sauer BM, Howe CL. (2011) The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures. Experimental Cell Research. 317: 1955-69
Rao AA, Ye H, Decker PA, et al. (2011) Therapeutic doses of cranial irradiation induce hippocampus-dependent cognitive deficits in young mice. Journal of Neuro-Oncology. 105: 191-8
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