Kathleen Griffioen, Ph.D.

Affiliations: 
The George Washington University, Washington, DC, United States 
Area:
nucleus ambiguus, cardiac
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"Kathleen Griffioen"
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Parents

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David Mendelowitz grad student 2007 The George Washington University
 (Cellular mechanisms of central cardiorespiratory responses to hypoxia.)
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Publications

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Griffioen K, Mattson MP, Okun E. (2018) Deficiency of Toll-like receptors 2, 3 or 4 extends life expectancy in Huntington's disease mice. Heliyon. 4: e00508
Okun E, Marton D, Cohen D, et al. (2017) Sirt6 alters adult hippocampal neurogenesis. Plos One. 12: e0179681
Wan R, Weigand LA, Bateman R, et al. (2014) Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability. Journal of Neurochemistry. 129: 573-80
Griffioen KJ, Wan R, Okun E, et al. (2011) GLP-1 receptor stimulation depresses heart rate variability and inhibits neurotransmission to cardiac vagal neurons. Cardiovascular Research. 89: 72-8
Dergacheva O, Griffioen KJ, Neff RA, et al. (2010) Respiratory modulation of premotor cardiac vagal neurons in the brainstem. Respiratory Physiology & Neurobiology. 174: 102-10
Dergacheva O, Griffioen KJ, Wang X, et al. (2007) 5-HT(2) receptor subtypes mediate different long-term changes in GABAergic activity to parasympathetic cardiac vagal neurons in the nucleus ambiguus. Neuroscience. 149: 696-705
Huang ZG, Griffioen KJ, Wang X, et al. (2007) Nicotinic receptor activation occludes purinergic control of central cardiorespiratory network responses to hypoxia/hypercapnia. Journal of Neurophysiology. 98: 2429-38
Griffioen KJ, Gorini C, Jameson H, et al. (2007) Purinergic P2X receptors mediate excitatory transmission to cardiac vagal neurons in the nucleus ambiguus after hypoxia. Hypertension. 50: 75-81
Griffioen KJ, Kamendi HW, Gorini CJ, et al. (2007) Reactive oxygen species mediate central cardiorespiratory network responses to acute intermittent hypoxia. Journal of Neurophysiology. 97: 2059-66
Huang ZG, Griffioen KJ, Wang X, et al. (2006) Differential control of central cardiorespiratory interactions by hypercapnia and the effect of prenatal nicotine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 21-9
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