Izumi Maezawa, Ph.D.

Affiliations: 
University of Washington, Seattle, Seattle, WA 
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"Izumi Maezawa"
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Thomas J. Montine grad student 2005 University of Washington
 (Glia-regulated, apolipoprotein E specific mechanisms of neuroprotection and neurodegeneration.)
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Publications

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Jin LW, Lucente JD, Nguyen HM, et al. (2019) Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. Annals of Clinical and Translational Neurology. 6: 723-738
Zhang L, Zhang S, Maezawa I, et al. (2019) Corrigendum to "Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease" [EBioMedicine 2 (2015) 294-305]. Ebiomedicine
Hilt S, Altman R, Kálai T, et al. (2018) A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta. Molecules (Basel, Switzerland). 23
Di Lucente J, Nguyen HM, Wulff H, et al. (2018) The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo. Glia
Chen YJ, Nguyen HM, Maezawa I, et al. (2018) Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke. Annals of Clinical and Translational Neurology. 5: 147-161
Jena PK, Sheng L, Di Lucente J, et al. (2018) Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201700984RR
Maezawa I, Nguyen HM, Di Lucente J, et al. (2017) Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept. Brain : a Journal of Neurology
Chen CY, Di Lucente J, Lin YC, et al. (2017) Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome. Neurobiology of Disease
Maezawa I, Zou B, Di Lucente J, et al. (2017) The Anti-Amyloid-β and Neuroprotective Properties of a Novel Tricyclic Pyrone Molecule. Journal of Alzheimer's Disease : Jad
Hilt S, Tang T, Walton JH, et al. (2016) A Metal-Free Method for Producing MRI Contrast at Amyloid-β. Journal of Alzheimer's Disease : Jad
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