Megan K. Houseweart, Ph.D.

Affiliations: 
University of California, San Diego, La Jolla, CA 
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"Megan Houseweart"
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Don Cleveland grad student 2000 UCSD
 (Investigation of methods to reduce motor neuron death in transgenic mouse models of amyotrophic lateral sclerosis.)
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Publications

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Houseweart MK, Vilaythong A, Yin XM, et al. (2003) Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death and Differentiation. 10: 1329-35
Houseweart MK, Pennacchio LA, Vilaythong A, et al. (2003) Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1). Journal of Neurobiology. 56: 315-27
Shannon P, Pennacchio LA, Houseweart MK, et al. (2002) Neuropathological changes in a mouse model of progressive myoclonus epilepsy: cystatin B deficiency and Unverricht-Lundborg disease. Journal of Neuropathology and Experimental Neurology. 61: 1085-91
Pasinelli P, Houseweart MK, Brown RH, et al. (2000) Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 13901-6
Houseweart MK, Cleveland DW. (1999) Cytoskeletal linkers: new MAPs for old destinations. Current Biology : Cb. 9: R864-6
Houseweart MK, Cleveland DW. (1999) Bcl-2 overexpression does not protect neurons from mutant neurofilament-mediated motor neuron degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6446-56
Pasinelli P, Borchelt DR, Houseweart MK, et al. (1998) Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 15763-8
Rao MV, Houseweart MK, Williamson TL, et al. (1998) Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation. The Journal of Cell Biology. 143: 171-81
Bruijn LI, Houseweart MK, Kato S, et al. (1998) Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science (New York, N.Y.). 281: 1851-4
Houseweart MK, Cleveland DW. (1998) Intermediate filaments and their associated proteins: multiple dynamic personalities. Current Opinion in Cell Biology. 10: 93-101
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