Andrea N. Flynn, Ph.D.
Affiliations: | University of Iowa, Iowa City, IA |
Area:
Cystic fibrosis, NeuroscienceGoogle:
"Andrea Flynn"Mean distance: 17.34 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Michael J. Welsh | grad student | 2008 | University of Iowa | |
| (Regulation of the paracellular pathway in human airway epithelia.) | ||||
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Publications
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| Boitano S, Hoffman J, Flynn AN, et al. (2015) The novel PAR2 ligand C391 blocks multiple PAR2 signaling pathways in vitro and in vivo. British Journal of Pharmacology |
| Flynn AN, Hoffman J, Tillu DV, et al. (2013) Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1498-510 |
| Hoffman J, Flynn AN, Tillu DV, et al. (2012) Lanthanide labeling of a potent protease activated receptor-2 agonist for time-resolved fluorescence analysis. Bioconjugate Chemistry. 23: 2098-104 |
| Flynn AN, Tillu DV, Asiedu MN, et al. (2011) The protease-activated receptor-2-specific agonists 2-aminothiazol-4-yl-LIGRL-NH2 and 6-aminonicotinyl-LIGRL-NH2 stimulate multiple signaling pathways to induce physiological responses in vitro and in vivo. The Journal of Biological Chemistry. 286: 19076-88 |
| Boitano S, Flynn AN, Sherwood CL, et al. (2011) Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR2. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L605-14 |
| Boitano S, Flynn AN, Schulz SM, et al. (2011) Potent agonists of the protease activated receptor 2 (PAR2). Journal of Medicinal Chemistry. 54: 1308-13 |
| Daines M, Flynn A, Sherwood C, et al. (2011) PAR-2 Activation by Alternaria alternata Proteases Induces Airway Epithelial Cell Activation and Lung Inflammation Journal of Allergy and Clinical Immunology. 127: AB59-AB59 |
| Flynn AN, Itani OA, Moninger TO, et al. (2009) Acute regulation of tight junction ion selectivity in human airway epithelia. Proceedings of the National Academy of Sciences of the United States of America. 106: 3591-6 |
| Flynn A, Itani O, Welsh M. (2008) Elevated Intracellular Calcium Transiently Increases Tight Junction Na+ Conductance in Human Airway Epithelia The Faseb Journal. 22: 132-132 |