Emily S. Walker, Ph.D.
Affiliations: | Washington University, Saint Louis, St. Louis, MO |
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=72Google:
"Emily Walker"Mean distance: 18.86 (cluster 28)
Parents
Sign in to add mentor| Alison M. Goate | grad student | 2005 | Washington University | |
| (Functional characterization of mutants of the Alzheimer's disease gamma-secretase enzyme complex.) | ||||
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Publications
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| Iacovazzo D, Flanagan SE, Walker E, et al. (2018) MAFA missense mutation causes familial insulinomatosis and diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America |
| Kakavand H, Walker E, Lum T, et al. (2016) BRAF(V600E) and NRAS(Q61L/Q61R) mutation analysis in metastatic melanoma using immunohistochemistry: a study of 754 cases highlighting potential pitfalls and guidelines for interpretation and reporting. Histopathology |
| Walker ES, Martinez M, Wang J, et al. (2006) Conserved residues in juxtamembrane region of the extracellular domain of nicastrin are essential for gamma-secretase complex formation. Journal of Neurochemistry. 98: 300-9 |
| Brunkan AL, Martinez M, Wang J, et al. (2005) Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and gamma-secretase activity. Journal of Neurochemistry. 94: 1315-28 |
| Brunkan AL, Martinez M, Walker ES, et al. (2005) Presenilin endoproteolysis is an intramolecular cleavage. Molecular and Cellular Neurosciences. 29: 65-73 |
| Brunkan AL, Martinez M, Wang J, et al. (2005) A domain at the C-terminus of PS1 is required for presenilinase and gamma-secretase activities. Journal of Neurochemistry. 92: 1158-69 |
| Walker ES, Martinez M, Brunkan AL, et al. (2005) Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios. Journal of Neurochemistry. 92: 294-301 |
| Wang J, Brunkan AL, Hecimovic S, et al. (2004) Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes. Neurobiology of Disease. 15: 654-66 |
| Walker ES, Martinez M, Brunkan A, et al. (2004) P4-309 Presenilin 2 familial Alzheimer's disease mutation decrease Aβ and CTFγ while differentially affecting NICD production Neurobiology of Aging. 25: S563 |