Nadim Jessani, Ph.D.

Affiliations: 
2004 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Medicinal Chemistry
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"Nadim Jessani"
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Benjamin F. Cravatt grad student 2004 Scripps Institute
 (The development and application of methods for activity-based protein profiling.)
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Publications

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Jessani N, Cravatt BF. (2008) Reverse Chemical Genetics Revisited: Chemical Strategies for Activity-based Proteomics Chemical Biology: From Small Molecules to Systems Biology and Drug Design, Volume 1-3. 1: 403-426
Jessani N, Niessen S, Wei BQ, et al. (2005) A streamlined platform for high-content functional proteomics of primary human specimens. Nature Methods. 2: 691-7
Jessani N, Young JA, Diaz SL, et al. (2005) Class assignment of sequence-unrelated members of enzyme superfamilies by activity-based protein profiling. Angewandte Chemie (International Ed. in English). 44: 2400-3
Jessani N, Niessen S, Mueller BM, et al. (2005) Breast cancer cell lines grown in vivo: what goes in isn't always the same as what comes out. Cell Cycle (Georgetown, Tex.). 4: 253-5
Jessani N, Humphrey M, McDonald WH, et al. (2004) Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo. Proceedings of the National Academy of Sciences of the United States of America. 101: 13756-61
Saghatelian A, Jessani N, Joseph A, et al. (2004) Activity-based probes for the proteomic profiling of metalloproteases. Proceedings of the National Academy of Sciences of the United States of America. 101: 10000-5
Jessani N, Cravatt BF. (2004) The development and application of methods for activity-based protein profiling. Current Opinion in Chemical Biology. 8: 54-9
Jessani N, Liu Y, Humphrey M, et al. (2002) Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness. Proceedings of the National Academy of Sciences of the United States of America. 99: 10335-40
Aboushadi N, Shackelford JE, Jessani N, et al. (2000) Characterization of peroxisomal 3-hydroxy-3-methylglutaryl coenzyme A reductase in UT2 cells: sterol biosynthesis, phosphorylation, degradation, and statin inhibition. Biochemistry. 39: 237-47
Engfelt WH, Shackelford JE, Aboushadi N, et al. (1997) Characterization of UT2 cells. The induction of peroxisomal 3-hydroxy-3-methylglutaryl-coenzyme a reductase. The Journal of Biological Chemistry. 272: 24579-87
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