Michele K. McKinney, Ph.D.
Affiliations: | 2006 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Medicinal ChemistryGoogle:
"Michele McKinney"Mean distance: 18.87 | S | N | B | C | P |
Parents
Sign in to add mentor| Benjamin F. Cravatt | grad student | 2006 | Scripps Institute | |
| (Catalytic mechanism and substrate selectivity of fatty acid amide hydrolase.) | ||||
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Publications
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| Grevengoed TJ, Trammell SAJ, McKinney MK, et al. (2019) -acyl taurines are endogenous lipid messengers that improve glucose homeostasis. Proceedings of the National Academy of Sciences of the United States of America |
| Kaczocha M, Lin Q, Nelson LD, et al. (2012) Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. Acs Chemical Neuroscience. 3: 364-8 |
| Saario SM, McKinney MK, Speers AE, et al. (2012) Clickable, photoreactive inhibitors to probe the active site microenvironment of fatty acid amide hydrolase(). Chemical Science (Royal Society of Chemistry : 2010). 3: 77-83 |
| Thors L, Burston JJ, Alter BJ, et al. (2010) Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. British Journal of Pharmacology. 160: 549-60 |
| Freigang S, Zadorozhny V, McKinney MK, et al. (2010) Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice. The Journal of Clinical Investigation. 120: 1873-84 |
| Ahn K, Johnson DS, Mileni M, et al. (2009) Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chemistry & Biology. 16: 411-20 |
| Ahn K, McKinney MK, Cravatt BF. (2008) Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. Chemical Reviews. 108: 1687-707 |
| Wei BQ, Mikkelsen TS, McKinney MK, et al. (2006) A second fatty acid amide hydrolase with variable distribution among placental mammals. The Journal of Biological Chemistry. 281: 36569-78 |
| McKinney MK, Cravatt BF. (2006) Structure-based design of a FAAH variant that discriminates between the N-acyl ethanolamine and taurine families of signaling lipids. Biochemistry. 45: 9016-22 |
| Saghatelian A, McKinney MK, Bandell M, et al. (2006) A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry. 45: 9007-15 |