Jae W. Chang, Ph.D.
Affiliations: | 2013 | Chemical Physiology | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Medicinal ChemistryGoogle:
"Jae Chang"Mean distance: 18.87 | S | N | B | C | P |
Parents
Sign in to add mentor| Benjamin F. Cravatt | grad student | 2013 | Scripps Institute | |
| (Development of Selective Chemical Probes for Functional Analysis of the Serine Hydrolases Superfamily.) | ||||
Children
Sign in to add trainee| Heung Sik Hahm | post-doc | 2020- | Emory University School of Medicine (Chemistry Tree) |
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Publications
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| Stein BD, Ferrarone JR, Gardner EE, et al. (2023) LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma. Cancer Discovery |
| Chang J, Bhuiyan M, Tsai HM, et al. (2020) In vivo imaging of the tumor-associated enzyme NCEH1 with a covalent PET probe. Angewandte Chemie (International Ed. in English) |
| Thoreen CC, Kang SA, Chang JW, et al. (2020) Correction: An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. The Journal of Biological Chemistry. 295: 2886 |
| Li G, Eckert MA, Chang JW, et al. (2019) Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation. Proceedings of the National Academy of Sciences of the United States of America |
| Huang JX, Lee G, Cavanaugh KE, et al. (2019) High throughput discovery of functional protein modifications by Hotspot Thermal Profiling. Nature Methods |
| Chang JW, Moellering RE. (2019) No Bones About It: Small Molecules for Bone Regeneration. Cell Chemical Biology. 26: 911-912 |
| Eckert MA, Coscia F, Chryplewicz A, et al. (2019) Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature |
| Bollong MJ, Lee G, Coukos JS, et al. (2018) A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature |
| Chang JW, Lee G, Montgomery JE, et al. (2018) Chemoproteomic Profiling of Phosphoaspartate Modifications in Prokaryotes. Angewandte Chemie (International Ed. in English) |
| Czarna A, Wang J, Zelencova D, et al. (2018) Novel scaffolds for Dual specificity tyrosine-phosphorylation-regulated kinase (DYRK1A) inhibitors. Journal of Medicinal Chemistry |