Pavitra S. Ramachandran, Ph.D.

Affiliations: 
2014 Genetics University of Iowa, Iowa City, IA 
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Parents

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Beverly L. Davidson grad student 2014 University of Iowa
 (RNA interference therapy for the spinocerebellar ataxias.)
Jean Bennett post-doc 2014-2017 Penn (Cell & Gene Therapy Tree)
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Publications

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Nikonov S, Aravand P, Lyubarsky A, et al. (2022) Restoration of Vision and Retinal Responses After Adeno-Associated Virus-Mediated Optogenetic Therapy in Blind Dogs. Translational Vision Science & Technology. 11: 24
Duong TT, Vasireddy V, Ramachandran P, et al. (2018) Use of induced pluripotent stem cell models to probe the pathogenesis of Choroideremia and to develop a potential treatment. Stem Cell Research. 27: 140-150
Aravand P, Ramachandran PS, Schpylchak I, et al. (2017) Protocols for Visually Guided Navigation Assessment of Efficacy of Retina-Directed Cell or Gene Therapy in Canines. Frontiers in Neuroscience. 11: 215
Ramachandran P, Lee V, Wei Z, et al. (2016) Evaluation of dose and safety of AAV7m8 and AAV8BP2 in the non-human primate retina. Human Gene Therapy
Ramachandran PS, Nikonov S, Willett K, et al. (2016) 270. Optogenetic Activation of Remnant Cone Cells Can Restore Ganglion Cell Light Responses in a Canine Model of Retinitis Pigmentosa Molecular Therapy. 24: S107
Leung A, Hua K, Ramachandran P, et al. (2015) C. elegans HAM-1 functions in the nucleus to regulate asymmetric neuroblast division. Developmental Biology
Ramachandran PS, Song JY, Bennett J. (2015) Exploiting metabolic and antioxidant pathways to maintain vision in blinding disease. The Journal of Clinical Investigation. 125: 1390-2
Ramachandran PS, Boudreau RL, Schaefer KA, et al. (2014) Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1635-42
Ramachandran PS, Bhattarai S, Singh P, et al. (2014) RNA interference-based therapy for spinocerebellar ataxia type 7 retinal degeneration. Plos One. 9: e95362
Ramachandran PS, Keiser MS, Davidson BL. (2013) Recent advances in RNA interference therapeutics for CNS diseases. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 473-85
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