Robert S. Freeman

University of Rochester, Rochester, NY 
Developmental Cell Ceath in the Nervous System
"Robert Freeman"
Mean distance: 16.15 (cluster 11)
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Papasergi-Scott MM, Stoveken HM, MacConnachie L, et al. (2018) Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange. Science Signaling. 11
Fernandes KA, Harder JM, Fornarola LB, et al. (2012) JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death. Neurobiology of Disease. 46: 393-401
Guo H, Barrett TM, Zhong Z, et al. (2011) Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway. Molecular Neurodegeneration. 6: 13
Zhong Z, Wang Y, Guo H, et al. (2010) Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15521-34
Xie L, Xiao K, Whalen EJ, et al. (2009) Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Science Signaling. 2: ra33
Guo Y, Schoell MC, Freeman RS. (2009) The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL). Oncogene. 28: 1864-74
Lomb DJ, Desouza LA, Franklin JL, et al. (2009) Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetic neurons. Molecular Pharmacology. 75: 1198-209
Ratan RR, Siddiq A, Aminova L, et al. (2008) Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. Annals of the New York Academy of Sciences. 1147: 383-94
Barone MC, Desouza LA, Freeman RS. (2008) Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity. Journal of Neurochemistry. 106: 734-45
Lomb DJ, Straub JA, Freeman RS. (2007) Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation. Journal of Neurochemistry. 103: 1897-906
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