Patty Kandalepas, Ph.D.

Affiliations: 
2009 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
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"Patty Kandalepas"
Mean distance: 17.58 (cluster 32)
 

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Martha Ulbrick Gillette grad student 2009 UIUC
 (Molecular mechanisms of melatonin action on the rat suprachiasmatic nucleus: An in vitro analysis.)
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Publications

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Kandalepas PC, Mitchell JW, Gillette MU. (2016) Melatonin Signal Transduction Pathways Require E-Box-Mediated Transcription of Per1 and Per2 to Reset the SCN Clock at Dusk. Plos One. 11: e0157824
Sadleir KR, Kandalepas PC, Buggia-Prévot V, et al. (2016) Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease. Acta Neuropathologica
Kandalepas PC, Vassar R. (2014) The normal and pathologic roles of the Alzheimer's β-secretase, BACE1. Current Alzheimer Research. 11: 441-9
Kandalepas PC, Sadleir KR, Eimer WA, et al. (2013) The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques. Acta Neuropathologica. 126: 329-52
Kandalepas PC, Vassar R. (2012) Identification and biology of β-secretase. Journal of Neurochemistry. 120: 55-61
Vassar R, Kandalepas PC. (2011) The β-secretase enzyme BACE1 as a therapeutic target for Alzheimer's disease. Alzheimer's Research & Therapy. 3: 20
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