Lauren A. Hirao, Ph.D.
Affiliations: | 2010 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
DNA vaccine, HIVGoogle:
"Lauren Hirao"Mean distance: 23748
Parents
Sign in to add mentor| David B. Weiner | grad student | 2010 | Penn | |
| (Enhancement of immune responses to DNA vaccines.) | ||||
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Publications
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| Weber MG, Walters-Laird CJ, Kol A, et al. (2021) Gut germinal center regeneration and enhanced anti-viral immunity by mesenchymal stem/stromal cells in SIV infection. Jci Insight |
| Crakes KR, Santos Rocha C, Grishina I, et al. (2019) PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. Proceedings of the National Academy of Sciences of the United States of America |
| Santos Rocha C, Hirao LA, Weber MG, et al. (2018) Subclinical cytomegalovirus infection associates with altered host immunity, gut microbiota and vaccine responses. Journal of Virology |
| Jiang G, Santos Rocha C, Hirao LA, et al. (2017) HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection. Mbio. 8 |
| Golomb BL, Hirao LA, Dandekar S, et al. (2016) Gene expression of Lactobacillus plantarum and the commensal microbiota in the ileum of healthy and early SIV-infected rhesus macaques. Scientific Reports. 6: 24723 |
| Glavan TW, Gaulke CA, Santos Rocha C, et al. (2015) Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. Mucosal Immunology |
| Glavan TW, Gaulke CA, Hirao LA, et al. (2015) SIV-infection-driven changes of pattern recognition receptor expression in mesenteric lymph nodes and gut microbiota dysbiosis. Journal of Medical Primatology. 44: 241-52 |
| Hirao LA, Grishina I, Bourry O, et al. (2014) Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption. Plos Pathogens. 10: e1004311 |
| Nagy LH, Grishina I, Macal M, et al. (2013) Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal Lactobacillus. Plos One. 8: e72789 |
| Hutnick NA, Myles DJ, Hirao L, et al. (2012) An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge. Vaccine. 30: 3202-8 |