Ming-Kuei Jang

Affiliations: 
Merck, Boston, Boston, MA, United States 
Area:
neurodegenerative diseases; synaptic functions; novel biomarker discovery
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"Ming-Kuei Jang"
Mean distance: 13.53 (cluster 11)
 
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Parents

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David H. Farb grad student 2003 Boston University
 (Molecular mechanisms for pregnenolone sulfate modulation of the N -methyl -D -aspartate receptor.)
Isabelle  M. Mintz post-doc 2003-2004 Northwestern
Steven A. Siegelbaum post-doc 2004-2006 Columbia University Medical School
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Publications

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Kostakis E, Smith C, Jang MK, et al. (2013) The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism. Molecular Pharmacology. 84: 261-74
Kostakis E, Jang MK, Russek SJ, et al. (2011) A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protons. Journal of Neurochemistry. 119: 486-96
Jang MK, Mierke DF, Russek SJ, et al. (2004) A steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 101: 8198-203
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