Jamie A. Jarusiewicz, Ph.D.

Affiliations: 
2012 Chemistry University of Southern California, Los Angeles, CA, United States 
Area:
synthetic organic chemistry
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Parents

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Nicos A. Petasis grad student 2012 USC
 (Synthesis of protein-protein interaction inhibitors and development of new catalytic methods.)
R. Kip Guy post-doc 2015-2016 St Jude Children's Research Hospital
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Publications

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Slavish PJ, Cuypers MG, Rimmer MA, et al. (2022) Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. European Journal of Medicinal Chemistry. 247: 115035
Rankovic Z, Min J, Mayasundari A, et al. (2021) Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs. Angewandte Chemie (International Ed. in English)
Nishiguchi G, Keramatnia F, Min J, et al. (2021) Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators. Journal of Medicinal Chemistry
Jarusiewicz JA, Jeon JY, Connelly MC, et al. (2017) Discovery of a Diaminopyrimidine FLT3 Inhibitor Active against Acute Myeloid Leukemia. Acs Omega. 2: 1985-2009
Jayathilaka N, Han A, Gaffney KJ, et al. (2012) Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2. Nucleic Acids Research. 40: 5378-88
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