Chong Han, Ph.D.
Affiliations: | 2010- | Small Molecule Process Chemistry | Genentech, Inc., San Francisco, CA, United States |
Area:
Synthesis of complex natural products; Cu, Pd, Zr-catalyzed transformationsGoogle:
"Chong Han"Mean distance: 8.1 | S | N | B | C | P |
Parents
Sign in to add mentor| John A. Porco | grad student | 2008 | Boston University | |
| (Synthesis of N-acyl vinylogous urea-containing natural products and development and applications of zirconium(IV)-catalyzed ester -amide exchange.) | ||||
| Stephen L. Buchwald | post-doc | 2008-2010 | MIT | |
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Publications
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| Xu J, Grosslight S, Mack KA, et al. (2022) Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Journal of the American Chemical Society |
| Zell D, Kingston C, Jermaks J, et al. (2021) Stereoconvergent and -divergent Synthesis of Tetrasubstituted Alkenes by Nickel-Catalyzed Cross-Couplings. Journal of the American Chemical Society. 143: 19078-19090 |
| Bigler R, Mack KA, Shen J, et al. (2019) Asymmetric Hydrogenation of Unfunctionalized, Tetrasubstituted, Acyclic Olefins. Angewandte Chemie (International Ed. in English) |
| Wong N, Petronijević F, Hong AY, et al. (2019) Stereocontrolled Synthesis of Arylomycin-Based Gram-Negative Antibiotic GDC-5338. Organic Letters |
| Han C, Alabanza LM, Kelly SM, et al. (2019) BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale Organic Process Research & Development. 23: 1695-1702 |
| Han C, Kelly SM, Cravillion T, et al. (2019) Synthesis of PI3K inhibitor GDC-0077 via a stereocontrolled N-arylation of α-amino acids Tetrahedron. 75: 4351-4357 |
| Savage S, McClory A, Zhang H, et al. (2018) Synthesis of Selective Estrogen Receptor Degrader GDC-0810 via Stereocontrolled Assembly of a Tetrasubstituted All-Carbon Olefin. The Journal of Organic Chemistry |
| Young IS, Glass AL, Cravillion T, et al. (2018) Palladium-Catalyzed Site-Selective Amidation of Dichloroazines. Organic Letters |
| Dalziel ME, Deichert JA, Carrera DE, et al. (2018) Magnesium Ethoxide Promoted Conversion of Nitriles to Amidines and Its Application in 5,6-Dihydroimidazobenzoxazepine Synthesis. Organic Letters |
| Lim NK, Cravillion T, Savage S, et al. (2018) Synthesis of a Selective Estrogen Receptor Degrader via a Stereospecific Elimination Approach. Organic Letters |