Norbert Perrimon
Affiliations: | 1986- | Genetics | Harvard University, Cambridge, MA, United States |
Website:
https://perrimon.med.harvard.edu/Google:
"Norbert Perrimon"Bio:
Dr. Perrimon has 30 years of experience in the fields of developmental genetics, signal transduction and genomics. By developing, improving, and applying a number of genetic techniques (germline clones, FLP/FRT, Gal4/UAS, etc.), his group identified many key components of the Receptor Tyrosine Kinases, JAK/STAT, Wnt, Hedgehog and Notch signaling pathways. In recent years, his group established high-throughput genome-wide RNAi screens to systematically interrogate the entire Drosophila genome in various cell-based assays. In 2003 he created the Drosophila RNAi Screening Center at Harvard Medical School to make this technology available to the community. In addition, in 2008, he initiated the Transgenic RNAi Project to generate transgenic RNAi lines for the community using optimized shRNA vectors that his lab developed. Currently, his laboratory is applying large-scale RNAi and proteomic methods to obtain a global understanding to the structure of a number of signaling pathways and their crosstalks. In addition, he is studying the roles of signaling pathways in homeostasis and tissue remodeling in Drosophila muscles and gut stem cells. Dr. Perrimon has trained more than 80 students and postdoctoral fellows, most of whom currently hold academic positions.
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Mean distance: 15.51 (cluster 11) | S | N | B | C | P |
Cross-listing: FlyTree - Computational Biology Tree
Parents
Sign in to add mentor| Madeleine Gans | grad student | 1983 | University of Paris VI (FlyTree) | |
| (Thesis: "Analyse Clonale de Mutations en Lignee Germinale chez la Drosophile") | ||||
| Anthony P. Mahowald | post-doc | 1983-1986 | Chicago (FlyTree) | |
Children
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You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Song S, Cho B, Weiner AT, et al. (2023) Protein phosphatase 1 regulates core PCP signaling. Embo Reports. e56997 |
| Song S, Cho B, Weiner AT, et al. (2023) Protein phosphatase 1 regulates core PCP signaling. Biorxiv : the Preprint Server For Biology |
| Petsakou A, Liu Y, Liu Y, et al. (2023) Cholinergic neurons trigger epithelial Ca currents to heal the gut. Nature |
| Petsakou A, Liu Y, Liu Y, et al. (2023) Epithelial Ca waves triggered by enteric neurons heal the gut. Biorxiv : the Preprint Server For Biology |
| Zirin J, Jusiak B, Lopes R, et al. (2023) Expanding the Drosophila toolkit for dual control of gene expression. Biorxiv : the Preprint Server For Biology |
| Ewen-Campen B, Luan H, Xu J, et al. (2023) split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304730120 |
| Xia B, Viswanatha R, Hu Y, et al. (2023) Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in cells. Elife. 12 |
| Ewen-Campen B, Luan H, Xu J, et al. (2023) split-intein Gal4 provides intersectional genetic labeling that is fully repressible by Gal80. Biorxiv : the Preprint Server For Biology |
| He L, Perrimon N. (2023) Synthetic Notch receptors and their applications to study cell-cell contacts in vivo. Developmental Cell. 58: 171-173 |
| Kim AR, Xu J, Cheloha R, et al. (2022) NanoTag Nanobody Tools for Drosophila In Vitro and In Vivo Studies. Current Protocols. 2: e628 |