Paul C. Chin, Ph.D.
Affiliations: | 2004 | University of Texas at Dallas, Richardson, TX, United States |
Area:
Neurodegenerative diseases, HDACsGoogle:
"Paul Chin"Mean distance: 18.08 (cluster 6)
Parents
Sign in to add mentor| Santosh D'Mello | grad student | 2004 | UT Dallas | |
| (Identification of molecular targets and drugs as potential therapies against neurodegenerative diseases.) | ||||
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Publications
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| Chin PC, Majdzadeh N, D'Mello SR. (2005) Inhibition of GSK3beta is a common event in neuroprotection by different survival factors. Brain Research. Molecular Brain Research. 137: 193-201 |
| Johnson K, Liu L, Majdzadeh N, et al. (2005) Inhibition of neuronal apoptosis by the cyclin-dependent kinase inhibitor GW8510: identification of 3' substituted indolones as a scaffold for the development of neuroprotective drugs. Journal of Neurochemistry. 93: 538-48 |
| D'Mello SR, Chin PC. (2005) Treating neurodegenerative conditions through the understanding of neuronal apoptosis. Current Drug Targets. Cns and Neurological Disorders. 4: 3-23 |
| Chin PC, D'Mello SR. (2005) Brain chemotherapy from the bench to the clinic: targeting neuronal survival with small molecule inhibitors of apoptosis. Frontiers in Bioscience : a Journal and Virtual Library. 10: 552-68 |
| Chin PC, D'Mello SR. (2004) Survival of cultured cerebellar granule neurons can be maintained by Akt-dependent and Akt-independent signaling pathways. Brain Research. Molecular Brain Research. 127: 140-5 |
| Chin PC, Liu L, Morrison BE, et al. (2004) The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism. Journal of Neurochemistry. 90: 595-608 |
| Meng F, Liu L, Chin PC, et al. (2002) Akt is a downstream target of NF-kappa B. The Journal of Biological Chemistry. 277: 29674-80 |