Ping-Chung Chen, Ph.D.

Affiliations: 
2010 Neurobiology University of Alabama, Birmingham, Birmingham, AL, United States 
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"Ping-Chung Chen"
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Scott Wilson grad student 2010 UAB
 (The role of USP14 in regulating synaptic development and function of the neuromuscular junctions.)
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Publications

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Vaden JH, Watson JA, Howard AD, et al. (2015) Distinct effects of ubiquitin overexpression on NMJ structure and motor performance in mice expressing catalytically inactive USP14. Frontiers in Molecular Neuroscience. 8: 11
Mertz J, Tan H, Pagala V, et al. (2015) Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth. Molecular & Cellular Proteomics : McP. 14: 1898-910
Vaden JH, Bhattacharyya BJ, Chen PC, et al. (2015) Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction. Molecular Neurodegeneration. 10: 3
Bai B, Hales CM, Chen PC, et al. (2013) U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16562-7
Hallengren J, Chen PC, Wilson SM. (2013) Neuronal ubiquitin homeostasis. Cell Biochemistry and Biophysics. 67: 67-73
Jin YN, Chen PC, Watson JA, et al. (2012) Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits. Plos One. 7: e47884
Chen PC, Bhattacharyya BJ, Hanna J, et al. (2011) Ubiquitin homeostasis is critical for synaptic development and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17505-13
Lee BH, Lee MJ, Park S, et al. (2010) Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature. 467: 179-84
Chen PC, Qin LN, Li XM, et al. (2009) The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10909-19
Crimmins S, Sutovsky M, Chen PC, et al. (2009) Transgenic rescue of ataxia mice reveals a male-specific sterility defect. Developmental Biology. 325: 33-42
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