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Jessica A. Bonzo, Ph.D.

Affiliations: 
2007 Biomedical Sciences University of California, San Diego, La Jolla, CA 
Area:
The role of environmental and chemical toxicants on gene expression
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"Jessica Bonzo"
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Robert H. Tukey grad student 2007 UCSD
 (Xenobiotic regulation of phase I and phase II metabolism enzymes: Beyond the Ah receptor paradigm.)

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Publications

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Zolfaghari R, Bonzo JA, Gonzalez FJ, et al. (2023) Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β () Gene in Hepatocytes. International Journal of Molecular Sciences. 24
Franzosa JA, Bonzo JA, Jack J, et al. (2021) High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures. Npj Systems Biology and Applications. 7: 7
Brocker CN, Kim D, Melia T, et al. (2020) Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting. Nature Communications. 11: 5847
Muthusamy S, Jeong JJ, Cheng M, et al. (2017) Hepatocyte Nuclear Factor 4α Regulates the Expression of Intestinal Epithelial Na(+)/H(+) Exchanger Isoform-3 (NHE3). American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00225.2017
Brocker CN, Yue J, Kim D, et al. (2017) Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from non-parenchymal cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00205.2016
Bonzo JA, Brocker C, Jiang C, et al. (2014) Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-α function in vivo. American Journal of Physiology. Endocrinology and Metabolism. 306: E824-37
Ciappio ED, Krausz KW, Rochman M, et al. (2014) Metabolomics reveals a role for the chromatin-binding protein HMGN5 in glutathione metabolism. Plos One. 9: e84583
Johnson CH, Manna SK, Krausz KW, et al. (2013) Global metabolomics reveals urinary biomarkers of breast cancer in a mcf-7 xenograft mouse model. Metabolites. 3: 658-72
Patterson AD, Carlson BA, Li F, et al. (2013) Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity. Chemical Research in Toxicology. 26: 1088-96
Wejksza K, Catalina LC, Bodogai M, et al. (2013) Cancer-produced metabolites of 5-lipoxygenase induce tumor-evoked regulatory B Cells via peroxisome proliferator-activated receptor α Journal of Immunology. 190: 2575-2584
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