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Mark Ptashne

Affiliations: 
Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States 
Area:
Cell Signaling; Gene Regulation; Stem Cell Biology
Website:
http://www.mskcc.org/research/lab/mark-ptashne
Google:
"Mark Ptashne"
Bio:

http://www.nasonline.org/member-directory/members/51474.html
http://www.mskcc.org/mskcc/html/10387.cfm
http://www.laskerfoundation.org/awards/1997_b_interview_ptashne.htm

Mean distance: 7.33 (cluster 13)
 		SNBCP
Cross-listing: FlyTree - GenetiTree - DevTree

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Parents

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Matthew S. Meselson grad student 1968 Harvard
 (Studies on lysogeny and conjugation in Escherichia coli)
Walter Gilbert post-doc 1965-1968 Harvard
 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC335506/)
James D. Watson post-doc 1965-1968 Harvard
 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC335506/)

Children

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Frederic D. Bushman grad student (Computational Biology Tree)
Edward Giniger grad student Harvard (Neurotree)
Liam Keegan grad student (FlyTree)
Jun Ma grad student (FlyTree)
Vincenzo Pirrotta grad student 1970 Harvard (FlyTree)
Barbara J. Meyer grad student 1979 Harvard (Neurotree)
Robert T. Sauer grad student 1979 Harvard
Alexander D. Johnson grad student 1980 Harvard
Carl O. Pabo grad student 1980 Harvard
Ann Hochschild grad student 1986 Harvard (Microtree)
Cynthia Wolberger grad student 1988 Harvard
Grace Gill grad student 1983-1989 Harvard
Pamela Reinagel grad student 1990-1994 Harvard (Neurotree)
Andrea H. Brand post-doc Harvard (Neurotree)
Tom Maniatis post-doc Harvard
Ronald W. Davis post-doc 1972 Harvard
Leonard Guarente post-doc 1981 Harvard (Cell Biology Tree)
Pamela A. Silver post-doc 1982-1985 Harvard
Aseem Z. Ansari post-doc 1998 Harvard
IM Bennani-Baiti research scientist Memorial Sloan Kettering Cancer Center

Collaborators

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BETA: Related publications

Publications

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Ptashne M. (2014) The chemistry of regulation of genes and other things. The Journal of Biological Chemistry. 289: 5417-35
Hammachi F, Morrison GM, Sharov AA, et al. (2012) Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency. Cell Reports. 1: 99-109
Wang X, Bai L, Bryant GO, et al. (2011) Nucleosomes and the accessibility problem. Trends in Genetics : Tig. 27: 487-92
Ptashne M. (2011) Principles of a switch. Nature Chemical Biology. 7: 484-7
Floer M, Wang X, Prabhu V, et al. (2010) A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding. Cell. 141: 407-18
Wang X, Muratani M, Tansey WP, et al. (2010) Proteolytic instability and the action of nonclassical transcriptional activators. Current Biology : Cb. 20: 868-71
Beckwith J, Herskowitz I, Ptashne M, et al. (2010) Political discussions at gordon conference. Science (New York, N.Y.). 171: 752
Bryant GO, Prabhu V, Floer M, et al. (2008) Activator control of nucleosome occupancy in activation and repression of transcription. Plos Biology. 6: 2928-39
Floer M, Bryant GO, Ptashne M. (2008) HSP90/70 chaperones are required for rapid nucleosome removal upon induction of the GAL genes of yeast. Proceedings of the National Academy of Sciences of the United States of America. 105: 2975-80
Ptashne M. (2005) Regulation of transcription: from lambda to eukaryotes. Trends in Biochemical Sciences. 30: 275-9
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