Darryll D. Dudley, Ph.D.

Affiliations: 
2003 Harvard University, Cambridge, MA, United States 
Area:
DNA repair, immunology, lymphoma
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"Darryll Dudley"
Mean distance: 16.75 (cluster 31)
 
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Frederick Alt grad student 2003 Harvard
 (Studies of the mechanisms directing recombination in B and T lymphocytes.)
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Publications

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Dudley DD, Wang HC, Sun XH. (2009) Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes. Plos One. 4: e6678
Dudley DD, Chaudhuri J, Bassing CH, et al. (2005) Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences. Advances in Immunology. 86: 43-112
Talukder SR, Dudley DD, Alt FW, et al. (2004) Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice. Nucleic Acids Research. 32: 4539-49
Dudley DD, Sekiguchi J, Zhu C, et al. (2003) Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice. The Journal of Experimental Medicine. 198: 1439-50
Akamatsu Y, Monroe R, Dudley DD, et al. (2003) Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 1209-14
Dudley DD, Manis JP, Zarrin AA, et al. (2002) Internal IgH class switch region deletions are position-independent and enhanced by AID expression. Proceedings of the National Academy of Sciences of the United States of America. 99: 9984-9
Manis JP, Dudley D, Kaylor L, et al. (2002) IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells. Immunity. 16: 607-17
Snapper SB, Takeshima F, Antón I, et al. (2001) N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nature Cell Biology. 3: 897-904
Wong DK, Dudley DD, Dohrenwend PB, et al. (2001) Detection of diverse hepatitis C virus (HCV)-specific cytotoxic T lymphocytes in peripheral blood of infected persons by screening for responses to all translated proteins of HCV. Journal of Virology. 75: 1229-35
Wong DK, Dudley DD, Afdhal NH, et al. (1998) Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection. Journal of Immunology (Baltimore, Md. : 1950). 160: 1479-88
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