Frank J. Smith, Ph.D.
Affiliations: | 2013 | Biochemistry | Temple University, Philadelphia, PA, United States |
Area:
K+ channelsGoogle:
"Frank Smith"Mean distance: 16.95 (cluster 46) | S | N | B | C | P |
Parents
Sign in to add mentor| Brad S. Rothberg | grad student | 2009-2013 | Temple University | |
| (Structural and functional analysis of the MthK potassium channel RCK domain.) | ||||
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Publications
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| Thomson AS, Heer FT, Smith FJ, et al. (2014) Initial steps of inactivation at the K+ channel selectivity filter. Proceedings of the National Academy of Sciences of the United States of America. 111: E1713-22 |
| Smith FJ, Pau VP, Cingolani G, et al. (2013) Structural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domain. Nature Communications. 4: 2621 |
| Blaydon DC, Lind LK, Plagnol V, et al. (2013) Mutations in AQP5, encoding a water-channel protein, cause autosomal-dominant diffuse nonepidermolytic palmoplantar keratoderma. American Journal of Human Genetics. 93: 330-5 |
| Smith FJ, Rothberg BS. (2013) Analysis of Ca(2+)-binding sites in the MthK RCK domain by X-ray crystallography. Methods in Molecular Biology (Clifton, N.J.). 998: 277-87 |
| Smith FJ, Rothberg BS. (2013) Crystal Structures of the MthK RCK Domain Reveal Allosteric Interactions Among Calcium Binding Sites Biophysical Journal. 104: 367a |
| Smith FJ, Pau VP, Cingolani G, et al. (2012) Crystal structure of a Ba(2+)-bound gating ring reveals elementary steps in RCK domain activation. Structure (London, England : 1993). 20: 2038-47 |
| Smith FJ, Pau VP, Taylor AB, et al. (2012) Multiple Ca2+ Binding Sites in the RCK Domain Contribute to Gating in the MthK K+ Channel Biophysical Journal. 102: 690a |
| Pau VP, Smith FJ, Taylor AB, et al. (2011) Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain. Proceedings of the National Academy of Sciences of the United States of America. 108: 17684-9 |