David A. Costa, Ph.D.

Affiliations: 
2005 University of South Florida, Tampa, FL, United States 
Area:
Alzheimer's Disease, Down Syndrome
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"David Costa"
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Huntington Potter grad student 2005 University of South Florida
 (Promoting and preventing Alzheimer's disease in a transgenic mouse model: Apolipoprotein E and environmental enrichment.)
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Publications

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Nilsson LN, Gografe S, Costa DA, et al. (2012) USE OF FUSED CIRCULATIONS TO INVESTIGATE THE ROLE OF APOLIPOPROTEIN E AS AMYLOID CATALYST AND PERIPHERAL SINK IN ALZHEIMER'S DISEASE. Technology and Innovation. 14: 199-208
Costa DA, Cracchiolo JR, Bachstetter AD, et al. (2007) Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms. Neurobiology of Aging. 28: 831-44
Arndash GW, Cracchiolo JR, Costa DA, et al. (2006) P4-322: Complete environmental enrichment is required to protect AD transgenic mice against cognitive impairment, reduce a-beta deposition, and increase synaptophysin staining: Involvement of both amyloid-dependent and independent mechanisms Alzheimer's & Dementia. 2: S611-S611
Potter H, Costa DA, Cracciola JR, et al. (2005) [O2-03-02]: Environmental enrichment prevents cognitive decline and induces memory-related gene expression in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 1: S99-S99
Costa DA, Nilsson LN, Bales KR, et al. (2004) Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 6: 509-14
Nilsson LN, Arendash GW, Leighty RE, et al. (2004) Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation. Neurobiology of Aging. 25: 1153-67
Arendash GW, Garcia MF, Costa DA, et al. (2004) Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition. Neuroreport. 15: 1751-4
Leighty RE, Nilsson LN, Potter H, et al. (2004) Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer's transgenic mouse lines differing in Abeta deposition. Behavioural Brain Research. 153: 107-21
Costa DA, Bales KR, Paul SM, et al. (2004) P2-302 Apolipoprotein E is required for filamentous, but not diffuse, amyloid deposition in an APP/PS mouse model of Alzheimer's disease Neurobiology of Aging. 25: S318-S319
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