James L. Hougland, Ph.D.

Affiliations: 
2005-2010 Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
 2010- Chemistry Syracuse University, Syracuse, NY, United States 
Area:
chemistry and biochemistryof nucleic acids
Website:
https://hougland.expressions.syr.edu/
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SNBCP

Parents

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Joseph A. Piccirilli grad student 2005 Chicago
 (Investigating the structural and functional basis of catalysis in the Tetrahymena group I ribozyme.)
Carol A. Fierke post-doc 2005-2010 University of Michigan

Children

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Joseph Edgar Darling grad student 2010-2015 Syracuse
Susan Clare Flynn grad student 2010-2015 Syracuse
Soumyashree A Gangopadhyay grad student 2011-2016 Syracuse
Kayleigh McGovern-Gooch grad student 2012-2017 Syracuse
Melanie Jane Blanden grad student 2011-2018 Syracuse
Elizabeth Rose Cleverdon grad student 2013-2018 Syracuse
Maria Campana grad student 2014-2020 Syracuse
Sudhat Ashok grad student 2015-2020 Syracuse
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Publications

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Justyna K, Das R, Lorimer EL, et al. (2023) Synthesis, Enzymatic Peptide Incorporation, and Applications of Diazirine-Containing Isoprenoid Diphosphate Analogues. Organic Letters
Campaña MB, Davis TR, Novak SX, et al. (2023) Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin -Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme. Acs Chemical Biology
Pierce MR, Hougland JL. (2023) A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound -acyltransferases. Frontiers in Physiology. 14: 1167873
Morstein J, Bader T, Cardillo AL, et al. (2022) Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation. Acs Chemical Biology
Hossain MS, Zhang Z, Ashok S, et al. (2022) Temperature-Responsive Nano-Biomaterials from Genetically Encoded Farnesylated Disordered Proteins. Acs Applied Bio Materials
Schey GL, Buttery PH, Hildebrandt ER, et al. (2021) MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase. International Journal of Molecular Sciences. 22
Davis TR, Pierce MR, Novak SX, et al. (2021) Ghrelin octanoylation by ghrelin -acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling. Open Biology. 11: 210080
Wang Y, Kilic O, Csizmar CM, et al. (2020) Engineering reversible cell-cell interactions using enzymatically lipidated chemically self-assembled nanorings. Chemical Science. 12: 331-340
Moose JE, Leets KA, Mate NA, et al. (2020) An overview of ghrelin -acyltransferase inhibitors: a literature and patent review for 2010-2019. Expert Opinion On Therapeutic Patents. 1-13
Ashok S, Hildebrandt ER, Ruiz CS, et al. (2020) Protein Farnesyltransferase Catalyzes Unanticipated Farnesylation and Geranylgeranylation of Shortened Target Sequences. Biochemistry
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