Melissa L. Blackman, Ph.D.

Affiliations: 
2011 Chemistry and Biochemistry University of Delaware, Newark, DE, United States 
Area:
Organic chemistry
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"Melissa Blackman"
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Joseph M. Fox grad student 2011 University of Delaware
 (The tetrazine ligation: Development of a novel bioorthogonal Diels-Alder reaction and its applications.)
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Publications

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Lang K, Davis L, Wallace S, et al. (2012) Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions. Journal of the American Chemical Society. 134: 10317-20
Seitchik JL, Peeler JC, Taylor MT, et al. (2012) Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes. Journal of the American Chemical Society. 134: 2898-901
Taylor MT, Blackman ML, Dmitrenko O, et al. (2011) Design and synthesis of highly reactive dienophiles for the tetrazine-trans-cyclooctene ligation. Journal of the American Chemical Society. 133: 9646-9
Li Z, Cai H, Hassink M, et al. (2010) Tetrazine-trans-cyclooctene ligation for the rapid construction of 18F labeled probes. Chemical Communications (Cambridge, England). 46: 8043-5
Blackman ML, Royzen M, Fox JM. (2008) Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity. Journal of the American Chemical Society. 130: 13518-9
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