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Timothy B. Durham, Ph.D.

Affiliations: 
2002 University of Notre Dame, Notre Dame, IN, United States 
Area:
chemical and enzymatic synthesis and study of biologically important, heteroatom-containing systems including amino acids, peptides, antibiotics, siderophores, and others
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"Timothy Durham"
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Parents

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Marvin J. Miller grad student 2002 Notre Dame
 (beta-Lactams as synthons to biologically relevant molecules.)
William R. Roush post-doc 2002-2004 University of Michigan

Children

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Publications

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Prentice KJ, Wendell SG, Liu Y, et al. (2017) CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis. Ebiomedicine
Nagy E, Liu Y, Prentice KJ, et al. (2017) Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid (CMPF) and Effects on In Vitro Insulin Secretion. Journal of Medicinal Chemistry
O'Sullivan MC, Durham TB, Valdes HE, et al. (2015) Dibenzosuberyl substituted polyamines and analogs of clomipramine as effective inhibitors of trypanothione reductase; molecular docking, and assessment of trypanocidal activities. Bioorganic & Medicinal Chemistry. 23: 996-1010
Durham TB, Blanchard N, Savall BM, et al. (2004) Total synthesis of formamicin. Journal of the American Chemical Society. 126: 9307-17
Durham TB, Roush WR. (2003) Stereoselective synthesis of functionalized precursors of the CDEF and CDE 2,6-dideoxy-tetra- and trisaccharide units of durhamycins A and B. Organic Letters. 5: 1875-8
Durham TB, Roush WR. (2003) Stereoselective synthesis of 2-deoxy-beta-galactosides via 2-deoxy-2-bromo- and 2-deoxy-2-iodo-galactopyranosyl donors. Organic Letters. 5: 1871-4
Durham TB, Miller MJ. (2003) An enantioselective synthesis of differentially protected erythro-alpha,beta-diamino acids and its application to the synthesis of an analogue of rhodopeptin B5. The Journal of Organic Chemistry. 68: 35-42
Durham TB, Miller MJ. (2003) Enantioselective synthesis of alpha-amino acids from N-tosyloxy beta-lactams derived from beta-keto esters. The Journal of Organic Chemistry. 68: 27-34
Durham TB, Miller MJ. (2003) Enantioselective Synthesis of α-Amino Acids from N-Tosyloxy β-Lactams Derived from β-Keto Esters. Cheminform. 34
Durham TB, Miller MJ. (2002) Conversion of glucuronic acid glycosides to novel bicyclic beta-lactams. Organic Letters. 4: 135-8
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