Jennifer M. Spaethling, Ph.D.

2010 University of Pennsylvania, Philadelphia, PA, United States 
Biomechanics, Traumatic Brain Injury
"Jennifer Spaethling"
Mean distance: 23.54 (cluster 52)


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David Meaney grad student 2010 Penn
 (Signaling leading to calcium-permeable AMPA receptors and their role in neuronal loss following mechanical injury.)
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Spaethling JM, Sanchez-Alavez M, Lee J, et al. (2015) Single-cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Dueck H, Khaladkar M, Kim TK, et al. (2015) Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation. Genome Biology. 16: 122
Cavanaugh DJ, Geratowski JD, Wooltorton JR, et al. (2014) Identification of a circadian output circuit for rest:activity rhythms in Drosophila. Cell. 157: 689-701
Lovatt D, Ruble BK, Lee J, et al. (2014) Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue. Nature Methods. 11: 190-6
Spaethling JM, Piel D, Dueck H, et al. (2014) Serotonergic neuron regulation informed by in vivo single-cell transcriptomics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 771-80
Spaethling JM, Eberwine JH. (2013) Single-cell transcriptomics for drug target discovery. Current Opinion in Pharmacology. 13: 786-90
Eberwine J, Lovatt D, Buckley P, et al. (2012) Quantitative biology of single neurons. Journal of the Royal Society, Interface / the Royal Society. 9: 3165-83
Spaethling J, Le L, Meaney DF. (2012) NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury. Neurobiology of Disease. 46: 646-54
Singh P, Doshi S, Spaethling JM, et al. (2012) N-methyl-D-aspartate receptor mechanosensitivity is governed by C terminus of NR2B subunit. The Journal of Biological Chemistry. 287: 4348-59
von Reyn CR, Spaethling JM, Mesfin MN, et al. (2009) Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10350-6
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