Xin Zhou, Ph.D.
Affiliations: | 2010 | Medicinal Chemistry | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
development of approaches that will deliver anticancers drug, proteins and nucleic acids to cancer tissues and not normal tissuesGoogle:
"Xin Zhou"Mean distance: 9.13 | S | N | B | C | P |
Parents
Sign in to add mentor| Carston R. Wagner | grad student | 2010 | UMN | |
| (Catalytic mechanism of the hamster arylamine N-acetyltransferase 2 (NAT2) and human histidine triad nucleotide binding protein 1 (HINT1).) | ||||
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Publications
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| Shah R, Maize KM, Zhou X, et al. (2017) Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry |
| Zhou X, Chou TF, Aubol BE, et al. (2013) Kinetic mechanism of human histidine triad nucleotide binding protein 1. Biochemistry. 52: 3588-600 |
| Zhou X, Herbst-Robinson KJ, Zhang J. (2012) Visualizing dynamic activities of signaling enzymes using genetically encodable FRET-based biosensors: From designs to applications Methods in Enzymology. 504: 317-340 |
| Zhou X, Zhang N, Liu L, et al. (2009) Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190. The Febs Journal. 276: 6928-41 |
| Cheng J, Zhou X, Chou TF, et al. (2009) Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection. Bioorganic & Medicinal Chemistry Letters. 19: 6379-81 |
| Chou TF, Baraniak J, Kaczmarek R, et al. (2007) Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins. Molecular Pharmaceutics. 4: 208-17 |
| Liu F, Zhang N, Zhou X, et al. (2006) Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation. Journal of Molecular Biology. 361: 482-92 |